The ISBGroup Blog

The ISBGroup Blog

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Here you can read about everything that's happening in the ISB Group.

Second Swedish Diabetes Summit

EventsPosted by ISB Group Fri, December 01, 2017 15:11:07

Last week some of us (Gunnar, William, Christian, Fredrik and Thea) went to Gothenburg to attend the Second Swedish Diabetes Summit. It’s a summit bringing together basic and clinical research.

We had a good time listening to some really interesting presentations with topics varying from treatment of metabolic diseases to artificial intelligence in health and diabetes. Gunnar was chairman for the session of AI and he and William also presented a poster each.


New Student - Josef

NewsPosted by ISB Group Thu, October 26, 2017 14:51:36

This autumn, we welcome another new student in our group: Josef Grännö

Hello, my name is Josef, I study medicine, and I’m here at ISB Group to do a project for my 6th semester.

My project is about glycemic management in patients admitted to the intensive care unit. During my time here I will compare different models that aim to be used as decision support systems to help ICU staff maintain the patient’s glucose levels in optimal range. I collaborate mainly with the GlucoSafe group that is based in Aarhus, Denmark.

When not desperately trying to understand mathematics I enjoy the outdoors, volleyball and amateur acting.

New student - Christian

NewsPosted by ISB Group Tue, October 17, 2017 13:10:22
This autumn, we welcome another new student in our group: Christian Simonsson


My name is Christian Simonsson and I will be doing my master thesis here in the ISB-group. I am a 5th year engineering biology student with my master’s profile being Materials and Sensors in Biomedince. For my master’s thesis I wanted to do something a bit different from what I have been doing the last two years. Since my Bachelor’s project was on the topic of systems biology, and since I have an interest in modeling (in biology and physiology ), I was very pleased when I was given the opportunity to do my thesis here in the ISB group.

Adiponectin, which is a hormone released by mature adipocyte has been shown to have an important role in the development of type-2 diabetes. However, the precise underlying mechanisms for the production and release of such hormones in adipocytes are not fully understood. Therefore, an ongoing project in the ISB group has been to use mathematical modeling to describe the exocytosis of white adipocytes to predict adiponectin secretion, making it possible to quantify the exocytosis and endocytosis rates. An article on the subject was recently published by William Lövfors et al and in my project I will make use of the model presented in this article. The goal is to extend the model to also describe the experimental data for adiponectin secretion induced through the activation of beta-adrenergic signaling pathways upon extracellular adrenalin stimulation. Hopefully this might contribute to creating a more complete framework for understanding the regulation of this important metabolic hormone.

New student

NewsPosted by ISB Group Tue, October 17, 2017 11:19:21

This autumn, we welcome another new student in our group: Sofie Johansson

Hi! I’m Sofie.

I graduated from medical school spring 2017. A few years ago I did my undergraduate project in another scientific group and subsequently kept working there for a while. I was mainly looking at cardiovascular risk factors among adolescents.

In spite of great supervision I wanted to try another scientific field and have now ended up as a student in the ISB group to work on a project in systems biology. My job at the moment is to build a model of the lactate metabolism in the brain.

New student - Victor

NewsPosted by ISB Group Tue, October 17, 2017 11:01:01

This autumn, we welcome another new student in our group: Victor Viberg

Hi, my name is Victor Viberg. I’m studying biomedical engineering at Linköping University, currently I’m working on my master thesis in the ISB-group at IMT.

The goal of my project is to create a model that can explain the metabolic fluxes of a cancer cell and how it differs from a regular healthy cell. Hopefully this new insight will help in developing more effective treatments for cancer. The model is based on isotropic labeling of metabolites, and it is the first time this type of data is available for a whole human cell. My work will build on the previous work of Nicolas Sundqvist.

New student - Thea

NewsPosted by ISB Group Mon, October 16, 2017 15:41:04
This autumn, we welcome another new student in our group: Thea Sandqvist


My name is Thea and I'm here in the ISB Group to do a project in systems biology for my 6th semester in Medicine.

My project is about insulin- and glucose metabolism in rodents switching between chow- and high fatty based-diets. The project is based on a multi-level-multi-scale model conducted by former ISB Group-member Niclas Berqqvist. My experimental data comes from Karin G. Stenkula and her research group in Lund.

Besides spending time at the office I enjoy an occational pain-au-chocolat (or two or five).

New student!

NewsPosted by ISB Group Thu, September 21, 2017 09:38:29

This autumn, we welcome a new student in our group: Valentin Kindesjö

​Hello! My name is Valentin Kindesjö. I started medical school at Linköping University in the spring of 2015 after studying a year and a half of biomedical engineering. For the autumn of 2017, I have found my way back to IMT to join ISB group for a project in mathematical modelling, where I will be continuing the work of previous students (most recently Johanna Fridberger and Thirza Poot) in expanding a multi-level model over the regulation of glucose, insulin and fatty acids, created by joining a glucose- and insulin model created by Dalla Man et al and a NEFA model, created by Jelic et al as an expansion on a model by Fianne Sips. I will be working to make the NEFA part of this model more physiologically correct. Hopefully, this work will bring us closer to finding out the exact role played by adipose tissue in maintaining the systemic energy homeostasis, and shed some light over the dynamic interplay between the different mechanism involved in the storage and release of fatty acids.

I am spending my autumn in Oxford, at the group of Fredrik Karpe, professor of metabolic medicine at the Oxford Centre for Diabetes, Endocrinology and Metabolism, who conducted the experiments where the data I will be using was collected.

Welcome to the ISB-group reunion party

EventsPosted by ISB Group Thu, November 10, 2016 12:03:02
On October 26, 2006 ~ 10 years ago! - Gunnar Cedersund defended his PhD thesis. This was the start of the process of creating the reseach group To celebrate the 10-year mark, we have decided to arrange on January 14th 2017 a reunion party for anyone who has been involved so far!

Event: Reunion

Location: Linköping (Specifics tbd)

Date: 14th January 2017

If you're interested in the current projects or how your past project has fared, you'll get the chance to catch up during the evening. We are also very interested in the path you've chosen, so if you can, please do join us and tell us what you have been up to since we last saw you in the group. The day will consist of some lectures and general social interactions with the chance to see what has happened with everyone in the day, and a BIG party in the evening.

In case your invitation got lost in the Internet, please contact us at to reserve. We hope to see you in Linköping in January!

The reunion committee

Gunnar Cedersund
Elin Nyman
Rikard Johansson
Karin Lundengård
Fredrik Eklund
Johanna Fridberger

PS. Below are some group pictures to help you reminisce.

Gunnar defending his thesis 2006.

ISB group 2010.

ISB group 2012.

ISB group 2015.

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